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Currently, CB-839 has been in phase I and phase II clinical trials on AML (ClinicalTrials.gov: NCT02071927, ClinicalTrials.gov: NCT03047993)

doi: 10.1016/J.IJBIOMAC.2024.131873 201 YangL.BajinkaO.JarjuP

After paclitaxel chemotherapy, GSH levels significantly decreased, and the decrease was more pronounced in patients with vitamin D deficiency compared to those without deficiency ( p = 0.017) (Figure 1)